Patent Portfolio

Our comprehensive patent portfolio is listed here for reference.
We maintain sublicenses for numerous iPS cell-related patents and patent applications, not limited to those from Kyoto University, but also from various other universities and research institutions.

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  • Differentiation

    • Mesenchymal stem cells (MSC)

    AJ314

    Method for producing mesenchymal stem cells

    The present invention relates to a method for producing mesenchymal stem cells, and more specifically to a method for producing mesenchymal stem cells using a medium composition containing a basal medium and an adrenocortical hormone.

    Pub. No.
    JP 2022-189188
    Pub. date
    2022/12/22
  • Differentiation

    • Heart (Myocardium)

    AJ305

    Method for producing mature cardiomyocytes

    The present disclosure relates to methods for producing mature cardiomyocytes, methods for inducing the maturation of cardiomyocytes, etc.

    Pub. No.
    WO2026/048885
    Pub. date
    2026/3/5
  • Drug Discovery / Therapy

    • Nerve (Neuron)

    AJ304

    Maturation promoter for stem cell-derived non-mature nerve cells, maturation promotion method, proliferation inhibitor, and proliferation suppression method

    The present invention relates to a maturation promoter, a maturation promoter method, a proliferation inhibitor, and a proliferation inhibitor method for immature nerve cells derived from stem cells.

    Pub. No.
    Pub. date
  • Drug Discovery / Therapy

    • Heart (Myocardium)

    AJ303

    Cardiac function improving agent

    This invention relates to a cardiac function improving agent. More specifically, it relates to a cardiac function improving agent including a fibroblast growth factor receptor (FGFR) inhibitor.

    Pub. No.
    WO2026/083624
    Pub. date
    2026/4/23
  • Drug Discovery / Therapy

    • Nerve (Neuron)

    AJ302

    Method for predicting prognosis of diseases caused by accumulation of abnormal protein

    The present invention relates to a method for predicting the effectiveness of an oral medication in a subject against a disease caused by the accumulation of abnormal proteins.  The present invention also relates to a method for assessing behavioral and psychological symptoms of dementia (BPSD). 

    Pub. No.
    JP 2026-042645
    Pub. date
    2026/3/11
  • Differentiation

    • Heart (Myocardium)

    AJ301

    Mature cardiomyocyte production method

    The present invention relates to a method for producing mature cardiomyocytes.

    Pub. No.
    WO2025/254117
    Pub. date
    2025/12/11
  • Differentiation

    • Pancreas

    AJ300

    Method for producing pancreatic beta cells

    The present invention relates to a method for producing pancreatic beta cells, pancreatic beta cells produced by the method, and uses of the pancreatic beta cells.

    Pub. No.
    WO2026/004991
    Pub. date
    2026/1/2
  • Others

    AJ299

    Nucleic acid aptamer, RNA molecule, pharmaceutical composition, and template DNA molecule

    The present invention relates to nucleic acid aptamers that function as RNA sequences that enable cap-independent translation of mRNA, RNA molecules comprising the nucleic acid aptamers, pharmaceutical compositions containing the RNA molecules, and template DNA molecules.

    Pub. No.
    WO2025/249560
    Pub. date
    2025/12/4
  • Drug Discovery / Therapy

    • Nerve (Neuron)

    AJ298

    Prophylactic drug/therapeutic drug for progressive supranuclear palsy

    The invention relates to a preventive and/or therapeutic agent for progressive supranuclear palsy (hereinafter, sometimes referred to as PSP). More specifically, it relates to a preventive and/or therapeutic agent for neurodegenerative diseases including PSP, which contains as an active ingredient a growth arrest and DNA damage-inducible protein 34 (hereinafter, sometimes referred to as GADD34; also known as protein phosphatase 1 regulatory subunit 15A; hereinafter, sometimes referred to as PPP1R15A, and GADD34 and PPP1R15A may be referred to together) inhibitor, such as guanabenz.

    Pub. No.
    WO2024/195858
    Pub. date
    2024/9/26
  • Others

    AJ297

    Axioloid-based modular bottom-up in vitro model of human post-gastrulation development

    The invention relates to a three-dimensional cellular aggregate termed axioloid generated in vitro from a pluripotent stem cell and to a method for producing the same.

    Pub. No.
    WO2025/070803
    Pub. date
    2025/4/3
  • Others

    AJ296

    Target-molecule-specific functional protein control system

    Theinvention relates to a target molecule-specific functional protein control system and method.

    Pub. No.
    WO2025/100390
    Pub. date
    2025/5/15
  • Differentiation

    • Mesenchymal stem cells (MSC)

    AJ295

    Method for producing neural crest cells

    The invention relates to a method for producing neural crest cells. More specifically, it elates to a method for producing neural crest cells, which includes a step of performing suspension culture of pluripotent stem cells under specific conditions, and uses of neural crest cells obtained by the method.

    Pub. No.
    WO2024/242069
    Pub. date
    2024/11/28

As for the patents and patent applications related to iPS cell technology, iPS Academia Japan, Inc. has been widely granted sublicensing rights not only from Kyoto University but also from several other universities and research institutions.
The number of patents and patent applications licensed to iPS Academia Japan, Inc. reached about 780 applications (about 200 families), of which about 520 applications have been issued as patents (in Japan, USA, Europe and other countries). (as of May 2022)

Please feel free to contact us if you are interested in such patent applications for licensing.

Our Licensors

  • AIST
  • KWANSEI GAKUIN UNIVERSITY
  • NAGASAKI UNIVERSITY
  • Accelerate Technologies Pte Ltd
  • GIFU UNIVERSITY
  • NAGOYA CITY UNIVERSITY
  • Accellta Ltd.
  • KYOTO UNIVERSITY
  • NIHON UNIVERSITY
  • JBiC
  • KOBE UNIVERSITY
  • YOKOHAMA CITY UNIVERSITY
  • OSAKA UNIVERSITY
  • CHIBA UNIVERSITY
  • National Institutes for Quantum Science and Technology
  • OKAYAMA UNIVERSITY
  • TOKYO WOMEN'S MEDICAL UNIVERSITY
  •  ...etc